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Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)

Flavonoids are natural biomolecules that are known to be effective antivirals. These biomolecules can act at different stages of viral infection, particularly at the molecular level to inhibit viral growth. Enterovirus A71 (EV-A71), a non-enveloped RNA virus, is one of the causative agents o fhand, foot and mouth disease (HFMD), which is prevalent in Asia. Despite much effort, no clinically approved antiviral treatment is available for children suffering from HFMD. Flavonoids from plants…

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COVID-19 and Flavonoids: Study Examines How Infection Can Be Minimized

HOUSTON, TX, May 05, 2020 /24-7PressRelease/ — A researcher at NXG Logic, LLC (www.nxglogic.com) recently completed a molecular dynamics study of 72 flavonoids found mostly in fruits and vegetables to identify which ones could potentially be used to treat COVID-19 disease. The findings are described in a preprint entitled “COVID-19 and Flavonoids: In Silico Molecular Dynamics Docking to the Active Catalytic Site of SARS-CoV…

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Inhibition of SARS-CoV 3CL protease by flavonoids

Coronaviruses (CoVs) are single-stranded RNA viruses with large,enveloped and positive senses that can infect both animals andhumans1. CoVs, along with Artierivirdae and Roniviridae, belongto the Coronaviridae family in the order Nidovirales. These CoVscan infect various hosts, including avian, swine and humans.Human coronaviruses (HCoVs) represent a major group of CoVsassociated with various respiratory diseases from common cold toserious pneumonia and bronchiolitis

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